Speaker: Dacheng Ren
Title: Biofilm Formation: A Problem When Bacteria Settle
Affiliation: Syracuse University
Date: Monday, November 19, 2007.
Place and Time: Room 204-B, Love Building, 3:30-4:30 pm.
Abstract. Biofilms are highly hydrated structures comprised of a polysaccharide matrix secreted by the bound bacterial cells. Such sessile communities are ubiquitous in natural, engineering, and medical environments. Due to significantly enhanced tolerance to antibiotics and disinfection treatments (up to 1000 times), biofilms cause serious problems such as persistent infections in humans as well as corrosion and equipment failure in industry. Biofilm formation is a dynamic process that is affected by many environmental factors and involves significant changes in gene expression. Thus, interdisciplinary efforts are necessary for understanding and controlling biofilm formation.
In this presentation, we will review the current understanding of biofilm physiology and the approaches used to study and control biofilm formation. Specifically, we will present our recent progress in biofilm control through surface modification and interruption of cell-cell signaling.